منابع مشابه
Lung bioavailability of generic and innovator salbutamol metered dose inhalers.
BACKGROUND The aim of this study was to determine whether significant differences exist in lung bioavailability between generic (Salamol, Salbulin) and innovator (Ventolin) formulations of inhaled salbutamol given by metered dose inhalers. METHODS Ten healthy volunteers of mean age 20.5 years with a forced expiratory volume in one second (FEV1) of 112.1% predicted were studied in a randomised...
متن کاملVolumatic usage: some generic salbutamol metered dose inhalers can be used.
BACKGROUND The 30 minute and 24 hour post-inhalation urinary excretion of salbutamol represents the relative amount of drug deposited in the lungs and total systemic absorption, respectively. Using this method two metered dose inhalers used with a Volumatic (Allen and Hanburys Ltd, UK) large volume spacer have been compared. METHOD Eleven healthy volunteers inhaled 4 x 100 micrograms salbutam...
متن کاملMetered-dose inhalers, dry powder inhalers, and transitions.
Since 1956, the pMDI has become the most commonly prescribed and used aerosol device in the world. While concerns about global warming have led to a worldwide ban of CFCs, new HFA-propelled pMDIs are in development, requiring an evolutionary transition in the technology. The phase-out of CFC-propelled pMDIs has stimulated the development of more efficient DPIs, but issues such as cost of device...
متن کاملMetered-dose inhalers and dry powder inhalers in aerosol therapy.
Inhaled drug delivery is an important part of the armamentarium of clinicians caring for patients with pulmonary disease. An increasing variety of metered-dose inhalers and dry powder inhalers are becoming available. This has been driven by the development of new formulations and the impending ban on chlorofluorocarbon propellants. The result is a proliferation of devices, resulting in a confus...
متن کاملMetered dose inhalers and spacer devices.
Easy to carry, highly effective and extremely safe, allowing accurate, consistent dose delivery, metered dose inhalers are the inhalation devices doctors and patients choose most readily the world over. Clinical response, however, may be affected by the inhalation technique used and the precise formulation in the canisters. The purpose of this review is to consider metered dose inhalers, add on...
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ژورنال
عنوان ژورنال: Thorax
سال: 1995
ISSN: 0040-6376
DOI: 10.1136/thx.50.5.590-a